Rat Stem Cells Regenerate Brain Tissues in Mice

Innovative research reveals rat stem cells can form functional neural circuits in mice, offering potential insights for treating brain diseases.

Two independent studies demonstrate rat stem cells can regenerate neural pathways in mice, potentially aiding in understanding and treating neurodegenerative diseases.
Researchers used CRISPR technology to enable rat cells to develop forebrains in mice, marking a significant advancement in interspecies cell integration.
The regenerated tissues include olfactory circuits, allowing chimeric mice to perform tasks like locating hidden cookies, illustrating functional integration.
The studies also explore the potential for interspecies organ transplants and the flexibility of brain development across different species.
These findings could inform future clinical applications and deepen our understanding of brain evolution and development.