Overview
- An 18-year-old in St-Mathias-sur-Richelieu died of acute diphenhydramine poisoning in December 2023, with toxicology confirming lethal levels of the drug.
- Coroner Vincent Denault’s report identifies diphenhydramine’s acute toxicity, including risks of respiratory depression and fatal cardiac arrhythmias, as key concerns.
- Denault’s recommendations include reclassifying oral diphenhydramine to require pharmacist oversight and tracking sales to mitigate misuse.
- The report references prior deaths linked to diphenhydramine misuse, including a 2020 spike tied to the Benadryl TikTok challenge.
- The Ordre des pharmaciens du Québec is currently reviewing the recommendation, with potential regulatory changes under consideration by provincial authorities.