Overview
- San Francisco improved to 11-4 with a fifth straight win as Brock Purdy went 25-of-34 for 295 yards with a career-high five touchdown passes and one interception.
- Purdy became the first 49ers quarterback with five or more touchdown passes in any game since Steve Young in Super Bowl XXIX.
- Christian McCaffrey rushed for 117 yards, topped 1,000 on the season and caught two scores as the 49ers extended a multi-game no-punt streak.
- Philip Rivers, 44, completed 23 of 35 passes for 277 yards with two touchdowns and one interception in his second game back, but Indianapolis fell to 8-7 with a fifth consecutive loss.
- Dee Winters sealed the outcome with a 74-yard pick-six, and the Colts’ defeat clinched AFC playoff berths for the Bills, Jaguars and Chargers.