Psilocybin Reduces Symptoms of Body Dysmorphic Disorder in Pilot Study

A single dose of the psychedelic compound found in magic mushrooms shows promise in enhancing brain connectivity and alleviating BDD symptoms.

Psilocybin, the active ingredient in magic mushrooms, significantly reduced symptoms in individuals with body dysmorphic disorder (BDD).
A pilot trial involving eight participants revealed that a single 25-milligram dose of psilocybin improved brain network connectivity.
Patients exhibited increased neural connectivity in regions governing executive functions and emotional processing after just one day.
Participants who showed the greatest neural connectivity improvements experienced the most significant symptom relief within a week.
Researchers emphasize the need for larger, placebo-controlled studies to confirm the efficacy and durability of psilocybin treatment for BDD.