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Prue Leith Says Two Months on Mounjaro Brought Side Effects, Not Weight Loss

The Great British Baking Show judge contrasts her experience with her husband's reported 28-pound loss.

Overview

  • Leith told The Times she lost her appetite completely over two months on Mounjaro yet saw no change on the scale.
  • She said the drug left her tired and that she stopped as soon as she could because it felt terrible and was costly.
  • Her husband, John Playfair, has lost about 28 pounds on the injections and now drinks less alcohol, she noted.
  • Mounjaro (tirzepatide) is a weekly injection approved for type 2 diabetes that can aid weight loss by reducing appetite and slowing digestion, with common side effects including nausea and diarrhea, according to the Cleveland Clinic.
  • Leith has previously argued that weight-loss jabs are the wrong answer because they may require lifelong use.