Prince Frederik of Nassau Dies at 22 After Battle with Rare Genetic Disease
The young royal, known for his resilience and advocacy, passed away from POLG, a mitochondrial disorder, leaving behind a legacy of compassion and determination.
- Prince Frederik of Nassau, a distant relative of the Grand Duke of Luxembourg, passed away on March 1, 2025, in Paris at the age of 22 due to POLG, a rare mitochondrial disease.
- Diagnosed at 14, Frederik spent his life raising awareness and funding research for POLG through the foundation he established in 2022.
- Frederik’s father, Prince Robert, shared an emotional tribute, recounting his son's final moments with family and his poignant question, 'Papa, are you proud of me?'
- The prince was remembered for his humor, compassion, and courage, even in his final days, as well as his efforts to support those with rare diseases.
- His family has pledged to continue Frederik’s work through the POLG Foundation, ensuring his mission to aid others lives on.
Madame Figaro 
Sud Ouest 