Overview

• The strip binds HMGB1 proteins from menstrual effluent via antibodies fixed on atomically thin borophene nanosheets.
• Water-based synthesis yields pristine, biodegradable borophene without using harsh organic solvents.
• The test successfully detected HMGB1 at low concentrations, which is vital for early-stage or asymptomatic endometriosis screening.
• The research appeared on the July 17 cover of ACS Central Science after clinical samples confirmed significantly elevated HMGB1 levels in patients’ menstrual blood.
• The team is preparing larger clinical trials and exploring embedding the sensor into menstrual products for discreet home monitoring.