Potential Blood Test for Early Alzheimer’s Diagnosis Shows Promising Results

New research identifies sex-specific biomarkers that could enable noninvasive detection of Alzheimer’s disease, particularly in women.

Researchers discovered that declining levels of acetyl-L-carnitine and free carnitine in blood closely correlate with Alzheimer’s severity, especially in women.
The study highlights significant sex differences, with women showing more pronounced declines in free carnitine levels compared to men.
Combining these blood biomarkers with traditional spinal fluid measures improved diagnostic accuracy for Alzheimer’s to 93%.
The findings open the possibility of developing a noninvasive blood test for early diagnosis and monitoring of Alzheimer’s disease progression.
Future research aims to explore therapeutic targets within the molecular pathways linked to carnitine metabolism and its role in brain function.