Overview

• Kick-off is 18:45 GMT (7:45pm BST) at Estádio José Alvalade, with UK coverage on Amazon Prime Video pay-per-view.
• Roberto Martínez is without João Neves and João Cancelo through injury, with Nuno Tavares called up and Nuno Mendes expected to start.
• Ireland travel with several absences but welcome Séamus Coleman back, expect Evan Ferguson to be available, and have Troy Parrott in contention.
• Portugal have opened Group F with wins in Armenia (5-0) and Hungary (3-2), while Ireland have one point from a draw with Hungary and a defeat in Armenia.
• Ireland coach Heimir Hallgrimsson says his team need “almost a perfect game,” as betting previews widely forecast a comfortable Portugal win and highlight Cristiano Ronaldo as a likely scorer.