Overview

• Participants in the eight-week Methylation Diet and Lifestyle study, comprising 43 men aged 50 to 72, followed a program that combined a plant-based regimen with exercise, sleep and stress-reduction guidelines.
• Daily intake of methyl adaptogen foods—turmeric, garlic, berries, rosemary, green tea and oolong tea—correlated with an average 2.04-year decrease in biological age measured by DNA methylation.
• The intervention also emphasized dark leafy greens, cruciferous vegetables, seeds, beets, lean meats and low-glycemic fruits while excluding dairy, grains, legumes and alcohol.
• Men whose cellular age exceeded their chronological age at baseline experienced the most pronounced reversals in epigenetic aging.
• Researchers observed unintentional weight loss among participants but found it did not predict age-reversal outcomes and recommended larger, more diverse studies to confirm these results.