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Pfizer Beats Q3 Estimates and Raises 2026 Outlook

Strong sales of launched and established drugs enabled Pfizer to raise its 2026 guidance, supporting an expanded multiyear cost-cutting program.

Overview

  • Pfizer reported third-quarter revenue of $16.58 billion and adjusted EPS of $0.87, results the company said topped analyst estimates after its Tuesday earnings release.
  • The company raised full-year 2026 guidance to $62 billion–$64 billion and lifted adjusted EPS guidance to $2.95–3.05 per share based on year-to-date performance.
  • Sales of non-COVID medicines led the upside, with Eliquis reaching $2.52 billion (about 25% growth) and strong gains from Padcev and other recently launched or acquired products.
  • COVID-19 product sales continued to decline sharply, with Paxlovid and Comirnaty reporting large year-over-year drops, and Pfizer plans roughly $9.7 billion in net cost savings through 2029 to offset those losses.
  • Cecile Guegan, who served as interim CFO since August, was named permanent chief financial officer as Pfizer reorients capital and R&D plans toward its broader drug portfolio.