Parasitic Infection Linked to Cancer-Related Gene Activity in Cervical Tissue
New research shows that Schistosoma haematobium infection and its treatment with praziquantel may increase cervical cancer risks, prompting calls for enhanced monitoring and alternative therapies.
- Schistosoma haematobium, a parasite traditionally linked to bladder cancer, has been found to trigger cancer-related gene activity in the cervical lining.
- A study of 39 Tanzanian women revealed that genetic changes in cervical tissue intensified after treatment with praziquantel, raising concerns about long-term cancer risks.
- Researchers identified nine genes linked to cancer that were altered by the infection, with additional changes observed post-treatment, including genes tied to inflammation and tissue remodeling.
- Experts recommend close post-treatment monitoring for women previously infected with S. haematobium and suggest exploring anti-inflammatory or immune-modulating therapies to mitigate risks.
- A larger follow-up study involving 180 women over 12 months is underway to confirm these findings and assess the broader implications for cervical cancer prevention.
New York Post 
Medical Xpress 