Overview

• Fernando Tatís Jr. powered the Padres' 3-2 victory over the Astros, scoring all three runs and hitting a tiebreaking solo homer in the seventh inning.
• Luis Arraez was taken to the hospital after a first-inning collision with Mauricio Dubón at first base, raising concerns about his health.
• The Astros tied the game in the fifth inning with an RBI single from Dubón and a sacrifice fly by Yordan Alvarez.
• Rookie Tirso Ornelas made his major league debut for the Padres during this tightly contested interleague series.
• The series finale will determine the winner of this matchup between two of MLB's early-season leaders.