Overview

• On July 5, Osbourne delivered a farewell concert seated on a throne as spinal injuries and advancing Parkinson’s compromised his mobility.
• He first exhibited Parkinsonian syndrome signs in 2007, received a formal diagnosis in February 2019 and publicly disclosed his condition in 2020.
• Persistent loss of smell affects 70–90% of Parkinson’s patients and often precedes tremors, highlighting the potential for earlier intervention.
• While incurable, Parkinson’s management relies on dopamine-targeting medications, deep brain stimulation and specialized physical and occupational therapies.
• The disorder affects more than 10 million people globally—about 1 million in the U.S.—and its incidence rises markedly with age.