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Overhauled CDC Panel Backs Limits on MMRV for Under-4s, Tables Hepatitis B Shift

The advisory votes cite a small seizure risk and now go to Acting CDC Director Jim O’Neill, leaving programs and insurers weighing what to cover.

Overview

  • ACIP voted 8–3, with one abstention, to recommend using separate MMR and varicella shots rather than the combined MMRV for children younger than 4, citing a roughly twofold rise in febrile seizures after the first MMRV dose in 12–23 month-olds.
  • CDC presenters reported an absolute risk of about 8 seizures per 10,000 after the first MMRV dose versus about 4 per 10,000 with separate shots, and pediatric experts noted such seizures are typically brief and not linked to long-term harm.
  • After initial confusion, a follow-up vote left Vaccines for Children coverage unchanged for early MMRV doses, even as broader coverage decisions by Medicaid and private plans remain under review.
  • A planned change to the timing of the hepatitis B birth dose was delayed and then tabled following questions about safety, effectiveness and wording; the panel did endorse universal hepatitis B testing in pregnancy.
  • The reconstituted committee—installed by HHS Secretary Robert F. Kennedy Jr. and criticized by major medical groups—also adopted a narrower COVID-19 stance urging people to consult clinicians rather than a universal recommendation, with practical access implications still unclear.