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Orexin Neurons Found to Influence Exercise Choices Over Snacking

ETH Zurich researchers uncover how brain chemicals impact decisions between physical activity and high-calorie foods.

  • Study in mice shows orexin neurons play a key role in choosing exercise over junk food.
  • Blocking orexin signals made mice opt for high-calorie food instead of running on a wheel.
  • Orexin activity spikes before mice decide to exercise or eat, indicating its role in decision-making.
  • Findings could lead to new strategies for promoting physical activity and addressing obesity.
  • Further research is needed to confirm these results in humans.
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