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Oprah's GLP-1 Push and Serena Williams' Ro Tie Raise New Questions Over Celebrity Weight-Loss Deals

Experts warn celebrity promotions risk blurring clinical care with marketing.

Overview

  • Serena Williams said on a podcast with Oprah Winfrey that she used Zepbound through telehealth provider Ro, where she serves as a brand ambassador and her husband, Alexis Ohanian, is an investor and board member.
  • Physicians quoted in new coverage described those financial links as potential conflicts of interest and cautioned that such endorsements can stray into surrogate marketing of prescription drugs.
  • Oprah Winfrey, promoting her new book, described regaining weight after stopping GLP-1 therapy and now frames the medications as long-term management similar to treating high blood pressure.
  • GLP-1 drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound were developed for diabetes but are widely used for weight loss, with reporting noting broad uptake in the U.S.
  • A Fox News medical columnist praised GLP-1 benefits but warned they are not cure-alls, noting common weight regain after discontinuation and urging clinician-led care focused on lifestyle as well as medication.