Overview
- Winfrey began using a GLP‑1 drug in 2023, says it quieted obsessive thoughts about food, and now works out about two hours six days a week.
- She reports losing interest in alcohol after starting treatment, describing herself as once able to “outdrink everyone at the table.”
- She typically injects weekly, sometimes spacing doses to 10–12 days, and has declined to name the specific brand.
- Side effects have been minimal, mainly digestive issues she manages with hydration and magnesium, and she advises starting doses slowly.
- She co‑wrote Enough with Yale obesity expert Dr. Ania M. Jastreboff, out Jan. 13, 2026, as research continues to show GLP‑1s can dampen cravings, including for alcohol.