Overview
- The new book, coauthored with Yale obesity specialist Dr. Ania M. Jastreboff, argues obesity is a relapsing biological condition rather than a willpower failure.
- Winfrey told Today she experienced constipation on a GLP-1 and manages it with water and magnesium, as her coauthor advised slow dose increases to reduce side effects.
- She said the intrusive “food noise” subsided within hours of her first dose and that she now treats the medication as one tool alongside daily hikes, resistance training, and diet.
- Winfrey disclosed she regained about 20 pounds after stopping the drug for a year, informing her decision to maintain therapy over time.
- A new conversation with Serena Williams highlights changing attitudes, as Williams describes initial skepticism about “shortcuts” before publicly supporting GLP-1 use and partnering with telehealth firm Ro.