Overview
- The CDC estimates NB.1.8.1 caused about 37% of U.S. COVID infections as of early June, with a possible range of 13%–68% due to limited sequencing data.
- WHO designated NB.1.8.1 a “variant under monitoring” on May 23 after it was detected in at least 22 countries and 14 U.S. states.
- Genetic analyses show NB.1.8.1 carries multiple spike protein mutations that boost transmissibility without evidence of increased severity.
- Current vaccines are expected to protect against both symptomatic and severe disease, though updated jabs will require large new trials before full approval, limiting access for healthy adults and children.
- Experts caution that fading immunity, increased travel and relaxed preventive measures could combine to drive a COVID uptick this summer.