Overview

• The unbeaten, top-15 matchup kicks at 3:30 p.m. ET on ABC in Oxford, with No. 4 LSU facing No. 13 Ole Miss.
• Sources say Trinidad Chambliss will make a third straight start at quarterback for Ole Miss as Austin Simmons continues to recover from an ankle injury.
• Chambliss has flashed dual-threat production, including 307 passing yards and 112 rushing yards in the win over Tulane.
• LSU lists lead back Caden Durham day-to-day after an ankle sprain, and the Tigers’ struggling run game meets an Ole Miss defense ranked last in the SEC against the run, per the AP.
• Lane Kiffin says LSU star Harold Perkins Jr. demands special attention as the Tigers lean on an upgraded defense; recent meetings were thrillers (Ole Miss 55-49 in 2023, LSU 29-26 in OT in 2024) and odds reflect a tight game with some picks favoring Ole Miss by a point or two.