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Older Age and Low Fitness Linked to Higher Arrhythmia Burden in Healthy Middle-Aged Adults

Researchers used exercise testing plus continuous ECG in 1,151 asymptomatic adults to quantify irregular beats.

Overview

  • Findings were presented at ESC Congress 2025 in Madrid by a Chaim Sheba Medical Center team led by Dr. Amit Moses.
  • Arrhythmia odds rose about 9% per year for atrial events and 4% for ventricular events, with a marked uptick starting at ages 50–54.
  • Lower aerobic fitness independently predicted higher atrial ectopy and complex atrial arrhythmias, while age also related to ventricular ectopy.
  • Continuous monitoring identified complex rhythms in the cohort: 32% supraventricular tachycardia, 4% atrial fibrillation, and 6% nonsustained ventricular tachycardia.
  • The authors proposed considering age-based screening from about 50 and underscored the observational design and male-heavy sample as key limitations requiring further study.