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OKAVA Begins First Trial of GLP-1 Implant for Obese Cats

The tiny exenatide device delivers up to six months of dosing to address hard-to-manage pet obesity.

Overview

  • The MEOW-1 study has started dosing, with plans to enroll at least 50 obese cats and to monitor outcomes over 12 weeks with an optional 12-week extension.
  • About two thirds of participants will receive the implant, which is placed under the skin and steadily releases a GLP-1 agonist for up to six months.
  • Investigators aim to assess safety, tolerability, and weight-loss efficacy, with initial results expected next summer.
  • Early lab work and a small proof-of-concept in healthy cats suggested weight loss, but effectiveness and broader safety in obese pets remain unproven.
  • OKAVA plans a larger study next summer and is targeting FDA approval in 2027–2028, with a stated pricing goal near $100 per month and future testing in dogs and other indications.