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Nutritional Quality Trumps Processing for Long-Term Heart, Diabetes and Mortality Risk

The finding from a large US cohort study suggests prioritizing nutrient-dense diets plus manufacturer reformulation over blanket avoidance of ultra-processed foods.

Overview

  • Researchers presented the results at Nutrition 2026 on Tuesday, July 28, 2026, after analyzing more than 200,000 U.S. adults tracked from the 1980s through the 2020s.
  • Across the cohorts about 26,209 people developed cardiovascular disease, roughly 21,000 developed type 2 diabetes, and 55,493 died, and risk tracked more closely with overall diet quality than with how processed foods were.
  • The team separated diet quality from processing using plant-based diet indices and NOVA categories and found similarly low or high risk within healthy and unhealthy diet groups regardless of processing level.
  • Researchers noted that some ultra-processed foods such as fortified wholegrain cereals, plant-based milks and yoghurts, canned beans and wholegrain bread can support a healthy diet while many UPFs remain nutritionally poor.
  • The study is observational and presented as a conference abstract, so authors recommend that guidelines focus on nutrient-dense eating patterns and on encouraging packaged-food reformulation rather than advising universal avoidance of UPFs.