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Novo Nordisk Revises 2025 Outlook as FDA Crackdown and Competition Reshape Wegovy Market

The Danish drugmaker expects U.S. Wegovy sales to recover in H2 2025 following FDA enforcement and a new CVS formulary deal, despite lowering growth forecasts due to compounding competition.

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Flags with the Novo Nordisk logo flutter outside their Danish company's offices in Copenhagen, Denmark, September 26, 2023. REUTERS/Tom Little/File Photo
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FILE PHOTO: A view shows the logo of Novo Nordisk at the company's office in Bagsvaerd, on the outskirts of Copenhagen, Denmark, March 8, 2024. REUTERS/Tom Little/File photo

Overview

  • Novo Nordisk reported a Q1 net profit of 29 billion Danish kroner, a 14% year-on-year increase, and 19% sales growth, though Wegovy sales fell short of analyst expectations.
  • The company reduced its 2025 sales growth forecast to 13–21%, citing competition from compounded GLP-1 drugs in the U.S. as a key factor dampening branded uptake.
  • U.S. compounding pharmacies, which captured about one-third of the obesity drug market, must cease unapproved Wegovy and Ozempic copies by May 22 following an FDA ruling.
  • Novo Nordisk anticipates a recovery in U.S. Wegovy sales in the second half of 2025, supported by FDA enforcement and a new CVS Caremark formulary prioritizing Wegovy over Eli Lilly's Zepbound starting July 1.
  • The FDA accepted Novo's application for an oral GLP-1 treatment, which could become the first daily pill for obesity if approved, with a decision expected later this year.