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Nobel Prize in Medicine Honors Brunkow, Ramsdell and Sakaguchi for Immune Tolerance Breakthrough

The committee recognized discoveries that reveal how regulatory T cells keep immune responses from turning against the body's own tissues.

Overview

  • The award was announced in Stockholm by the Nobel committee and confirmed by the official Nobel Prize account.
  • Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi identified regulatory T cells as key controllers that prevent self-directed immune attacks and underpin advances in treating autoimmune disease and cancer, according to the committee.
  • This year’s distinction includes a gold medal, a diploma and 11 million Swedish kronor in prize money, with the formal ceremony scheduled for December 10 in Stockholm.
  • The medicine prize opens Nobel week, with physics, chemistry, literature, peace and economics awards to be named over the coming days.
  • Coverage also highlights worries over U.S. research funding, citing Grant Watch data that the NIH has canceled about 2,100 grants since January, a trend Swedish science leaders warn could erode scientific leadership.