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No. 6 Duke Visits No. 20 Louisville Tonight in Top-25 ACC Clash

Bookmakers shade Duke by about a point, with Louisville missing freshman point guard Mikel Brown Jr.

TALLAHASSEE, FL - JANUARY 03: Cayden Boozer #2 and Cameron Boozer #12 of the Duke Blue Devils look on during the first half of the game against the Florida State Seminoles at the Donald L. Tucker Center on January 3, 2026 in Tallahassee, Florida. The 6th ranked Blue Devils defeated the Seminoles 91-87. (Photo by Don Juan Moore/Getty Images)
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Overview

  • Tipoff is set for 7 p.m. ET at the KFC Yum! Center, with national coverage on ESPN and streaming in the ESPN app.
  • No. 6 Duke enters 13-1 (2-0 ACC) and has won seven straight in the series; No. 20 Louisville is 11-3 (1-1) and unbeaten at home this season.
  • Freshman Cameron Boozer paces Duke at 23.0 points and 9.8 rebounds per game, and Isaiah Evans is coming off a career-high 28 points in Saturday’s win at Florida State.
  • Louisville’s high-powered offense averages 90.4 points and ranks among the nation’s leaders in made threes, but Brown remains out with a back injury and Kasean Pryor has not played since Dec. 20.
  • Betting markets list Duke around -1 to -1.5 with a total near 161.5–162.5, while SportsLine’s model projects roughly 158 points and gives the Blue Devils a modest win probability.