Overview

• Ole Miss will start Division II transfer Trinidad Chambliss for a third straight game as Austin Simmons continues to deal with an ankle issue, according to multiple reports.
• Chambliss has delivered dual‑threat production with back‑to‑back 300‑plus yard passing games and 195 rushing yards with two scores across his starts.
• LSU running back Caden Durham, who sprained his ankle last week, is described by Brian Kelly as trending toward playing, a key note against an Ole Miss run defense ranked last in the SEC.
• Lane Kiffin highlighted Harold Perkins Jr.’s game‑changing impact as LSU leans on an upgraded defense stocked with transfer additions under coordinator Blake Baker.
• Kickoff is Saturday at 3:30 p.m. ET at Vaught‑Hemingway Stadium on ABC, with some projections narrowly backing Ole Miss following two recent high‑scoring meetings between these programs.