Overview

• Kickoff is 7:30 p.m. ET at Memorial Stadium in Clemson on ABC, with Chris Fowler and Kirk Herbstreit expected to call the game.
• Sportsbooks list Clemson by roughly 3.5–4.5 points with a total in the mid‑50s and moneyline ranges near Clemson -175 to -190 and LSU +150 to +160, reflecting line movement toward the home team.
• Analytical models project a close contest, with ESPN’s FPI giving Clemson about a 54% win probability and several predictions pointing to a one‑possession game.
• Quarterbacks Cade Klubnik and Garrett Nussmeier enter as Heisman and NFL draft contenders after 2024 seasons of 3,639 yards and 36 TDs for Klubnik and 4,052 yards and 29 TDs for Nussmeier.
• Previews highlight Clemson’s continuity, new DC Tom Allen, and a loaded defensive front led by T. J. Parker and Peter Woods against LSU’s portal‑boosted roster and an offensive line undergoing significant turnover, with the long‑running 'Death Valley' nickname dispute adding theater.