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No. 3 Penn State Hosts No. 6 Oregon in White Out Rematch Framing the CFP Race

Oddsmakers lean toward the home side, reflecting confidence in Jim Knowles’ retooled defense against Oregon’s explosive offense.

Will the Washington Huskies beat the Ohio State Buckeyes on Saturday? Big Ten football predictions, picks, odds preview the college football Week 5 game on Sept. 27, 2025.
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Overview

  • The matchup reprises last season’s Big Ten title game that Oregon won 45-37, offering an early barometer for both contenders’ postseason trajectories.
  • Penn State is priced around a 3.5-point favorite with a total near 52.5, and the primetime kickoff airs at 7:30 p.m. ET on NBC/Peacock.
  • ESPN’s College GameDay will be on site for the White Out, with Penn State pushing for one of the largest Beaver Stadium crowds on record.
  • Penn State invested in former Ohio State coordinator Jim Knowles, now the nation’s highest-paid assistant, to elevate a defense complementing a run-first attack led by Nicholas Singleton and Kaytron Allen.
  • Oregon counters with a prolific offense under quarterback Dante Moore, who has drawn Heisman attention, and running back Noah Whittington is expected to return; analysts also note Beaver Stadium’s grass surface as a potential variable for the turf-accustomed Ducks.