Overview

• Michigan State (3-0) visits No. 25 USC (3-0, 1-0) on Saturday at 11 p.m. ET at the Los Angeles Memorial Coliseum, with the game televised on FOX.
• Betting markets list USC as roughly an 18.5-point favorite, and local previews largely predict a double-digit Trojans win.
• Spartans coach Jonathan Smith said WR Nick Marsh and RB Makhi Frazier will be evaluated late in the week, while MSU also lists OL Luka Vincic as questionable and USC has multiple defensive backs out or questionable.
• USC enters with elite production, ranking first nationally in total offense and second in scoring, while its defense is among the leaders in sacks and tackles for loss.
• MSU QB Aidan Chiles is coming off season highs in passing and rushing, but protection has been inconsistent, and the program has not won a regular-season road game out West since 1984.