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Nighttime Caffeine Heightens Impulsive Behavior in Fruit Flies

Evening caffeine disrupts inhibitory control in fruit flies, with females displaying disproportionate impulsivity as researchers begin probing genetic factors.

Stock image of a man drinking coffee at night while working.
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Overview

  • The study, published in iScience on July 24, showed that fruit flies given caffeine at night were less able to suppress movement in response to strong airflow, demonstrating increased impulsivity.
  • Daytime caffeine consumption had no effect on flies’ inhibitory control, underscoring a time-dependent impact of caffeine.
  • Female flies exhibited substantially greater caffeine-induced reckless flying than males despite similar body caffeine levels.
  • Researchers noted that the absence of human-like hormones in Drosophila points to genetic or physiological factors behind the heightened female response.
  • The UTEP team plans to pinpoint the specific genetic pathways involved and warns that night-shift workers, especially women, may face elevated risks from late-night caffeine intake.