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NHS to Gradually Roll Out Mounjaro Weight-Loss Drug Over 12 Years

Only 10% of eligible patients in England will initially access the treatment due to phased rollout prioritizing those with highest clinical need.

  • Mounjaro, also known as tirzepatide and developed by Eli Lilly, has been approved by NICE for use in patients with a BMI over 35 and at least one weight-related health condition.
  • The phased rollout will prioritize 220,000 patients receiving care from specialist weight-management services over the next three years, with broader access planned over a 12-year period.
  • The decision to limit initial access was made to protect other NHS services and to evaluate how to safely and effectively implement the drug’s distribution.
  • Clinical trials showed Mounjaro achieved significant weight loss, with patients losing an average of 20% of body weight, surpassing results from similar drugs like semaglutide.
  • Health officials emphasize that Mounjaro must be taken alongside lifestyle changes, including a reduced-calorie diet and increased physical activity, and warn of potential side effects such as nausea and indigestion.
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