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NHS Reiterates Paracetamol Safety Advice, Highlighting Risks for Warfarin Users

The guidance urges the lowest effective dose with careful checks for hidden paracetamol.

Overview

  • The NHS says regular warfarin users face a higher risk of bleeding when taking paracetamol and should seek medical advice.
  • Taking more than four 500mg tablets in 24 hours for longer than a few days may slow blood clotting and increase bleeding risk.
  • People should avoid co-codamol or cold and flu products that also contain paracetamol to prevent accidental overdose.
  • Those on treatment for epilepsy or tuberculosis are advised to consult a GP or pharmacist before using paracetamol.
  • Severe allergic reactions are rare at recommended doses, but the NHS advises calling 999 if symptoms of anaphylaxis occur.