Overview

• The programme recruited patients across 20 NHS sites and integrated pharmacogenomic data into electronic health records in both GP practices and hospitals.
• Genetic testing identified actionable variants affecting common medications in 95% of the first 500 participants.
• Clinicians adjusted prescriptions to safer or more effective therapies for over one in four patients based on genomic guidance.
• The informatics solution is compatible with multiple genetic testing platforms and major EHR systems, enabling seamless clinical workflow integration.
• Researchers will next assess how pharmacogenomic-informed prescribing influences follow-up appointments, emergency visits and overall medication costs.