Overview
- Omeprazole, a proton pump inhibitor, is used for acid reflux, heartburn, indigestion, GORD, and with antibiotics for Helicobacter pylori.
- Common side effects include headache, stomach pain, nausea or vomiting, constipation or diarrhoea, and increased flatulence.
- Serious problems are uncommon but become more likely after about a year of use, including very low vitamin B12, weakened bones, allergic reactions, and lupus‑type rashes with joint pain.
- Patients are told to call 111 if they suspect serious reactions, to consult a pharmacist or doctor about persistent side effects, and to continue treatment unless advised otherwise.
- Some formulations are available over the counter for short courses of up to two weeks, with most requiring a prescription, and the NHS directs people to the leaflet or the electronic medicines compendium for full details and to the Yellow Card website to report side effects.