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NHS Delivers First Histotripsy Treatment in Europe at Addenbrooke’s

An MHRA early-access authorisation opens a tightly controlled, philanthropically funded rollout at Cambridge.

Overview

  • Roger Jackson, 80, received the incisionless ultrasound procedure for liver cancer and was discharged the following day.
  • Consultant interventional radiologist Dr Teik Choon See led the treatment, which uses focused ultrasound bubble clouds to mechanically destroy tumour tissue without surgery, radiation or chemotherapy.
  • The device is operating under an Unmet Clinical Need Authorisation within the MHRA’s Innovative Devices Access Pathway, enabling time-limited early use under specified conditions.
  • The Edison system, developed by HistoSonics, was installed via a Li Ka Shing Foundation donation and follows 2023 FDA clearance with more than 2,000 patients treated worldwide.
  • Addenbrooke’s is establishing referral pathways and initially offering the therapy to selected primary and secondary liver cancer patients with ACT support, while NIHR explores research funding, and no other UK provider currently offers histotripsy.