NFL Week 12 Preview: Key Betting Trends and Expert Predictions

As Week 12 approaches, analysts highlight top teams against the spread, underdog picks, and notable matchups shaping the NFL landscape.

The Detroit Lions (9-1) and Pittsburgh Steelers (8-2) lead the league in against-the-spread (ATS) performance at 8-2, with both teams favored in their Week 12 matchups against the Colts and Browns, respectively.
The Tennessee Titans (1-9 ATS) and Dallas Cowboys (2-8 ATS) remain the least reliable teams for bettors, with the Titans entering their game against the Texans as 8-point underdogs.
Analysts are divided on several key matchups, including the Steelers vs. Browns and Dolphins vs. Patriots, with weather and recent team trends influencing predictions.
The Indianapolis Colts (8-3 ATS) are highlighted as a strong underdog pick against the Lions, with their defense's ability to force turnovers and QB Anthony Richardson's mobility posing potential challenges.
Upcoming divisional contests, including the Ravens vs. Chargers and Cardinals vs. Seahawks, are expected to have significant playoff implications as teams jostle for positioning in tight races.