Philadelphia hosts Dallas on Sept. 4 at 8:00 p.m. ET on NBC with streaming on Peacock and NFL+, with Mexico broadcasts listed on Disney+ Premium, ESPN2, Canal 9 and NFL Game Pass. Week 1 features a Friday game in São Paulo as the Chiefs face the Chargers on Sept. 5, streamed on YouTube. New measures include a dynamic kickoff, overtime that guarantees each team a possession, expanded replay assistance for clear errors, and Hawk-Eye virtual measurements. Twelve franchises open with a different starting quarterback than in Week 1 of 2024, underscoring broad roster turnover to start the season. Dallas enters with defensive questions after departures of Micah Parsons and DeMarcus Lawrence, while betting markets tab the Eagles, Bills and Ravens among early Super Bowl LX favorites.