Overview
- Josef Newgarden posted the fastest lap of 226.632 mph in Thursday's practice, solidifying his position as the benchmark heading into Fast Friday.
- Scott Dixon, aiming for a record-tying sixth Indy 500 pole, recorded the second-fastest lap at 225.457 mph but faces a penalty for a second engine change.
- Honda confirmed plans to swap engines for all its full-time entries, with Dixon's penalty to take effect at the next race in Detroit.
- Christian Rasmussen spun exiting Turn 2 but avoided major damage, continuing practice after minimal repairs to his car.
- Kyle Larson, preparing for his ambitious Indy-Charlotte 'Double,' ranked 17th in practice and reported progress in adapting to the car.