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Newborn on Martha’s Vineyard Shows Early Neurological Gains After Rare Powassan Virus Infection

Martha’s Vineyard officials are investigating the island’s second Powassan case in 20 years following a newborn’s hospitalization at Massachusetts General Hospital.

A deer tick after being pulled from a Massachusetts woman’s neck. Left unchecked, deer ticks can transmit Lyme disease to humans.
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Overview

  • Lily Sisco, a newborn from West Tisbury, is critically ill at Massachusetts General Hospital with encephalitis but has begun to show gradual neurological improvement after contracting Powassan virus.
  • The Martha’s Vineyard Boards of Health confirmed it as the island’s second Powassan case in 20 years and the fourth in Massachusetts this year, prompting local investigations into exposure sources.
  • Powassan virus is transmitted by deer ticks within 15 minutes of a bite, can cause severe brain inflammation and seizures, and has a fatality rate of roughly 10% with no specific treatment or vaccine.
  • Emergency department visits for tick bites in the Northeast are at a five-year high, driven by milder winters and expanding deer populations that increase human–tick encounters.
  • Public health agencies are urging year-round tick-bite prevention measures such as using EPA-approved repellents, treating clothing with permethrin, performing daily tick checks, and staying on clear trails.