New Tool to Track CRISPR Editing Risks Developed

Researchers at UC San Diego create a genetic analysis tool, enhancing the safety of CRISPR-based therapies.

Researchers at the University of California San Diego develop the Integrated Classifier Pipeline (ICP), a new genetic analysis tool to track CRISPR editing risks.
ICP provides detailed insights into on- and off-target CRISPR mutational edits and their inheritance, potentially improving the safety of gene therapies.
Developed in flies and mosquitoes, the ICP system can distinguish if genetic components of CRISPR machinery are inherited from the mother or father.
The tool has broad applications, including tracking inheritance in gene drive systems and analyzing CRISPR editing outcomes in humans.
ICP's development marks a significant step in ensuring the safe application of CRISPR in health technologies and agriculture.