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New Test Achieves Over 90% Accuracy in Predicting Bowel Cancer Risk for IBD Patients

The UK-developed algorithm could lead to a blood test, helping high-risk patients with Crohn's and colitis manage their cancer risk more effectively.

Overview

  • Researchers at the Institute of Cancer Research (ICR) in the UK have developed a test that predicts bowel cancer risk with over 90% accuracy in patients with inflammatory bowel disease (IBD).
  • The algorithm analyzes DNA changes in pre-cancerous cells to identify individuals most likely to develop bowel cancer within five years.
  • The test aims to reduce the need for frequent colonoscopies and unnecessary surgeries by providing personalized risk assessments for patients with Crohn's disease and ulcerative colitis.
  • Scientists hope to translate this research into a simple blood test, making early detection and intervention more accessible in clinical settings.
  • The study, funded by Cancer Research UK, highlights the potential for cost savings in healthcare and improved quality of life for patients by focusing resources on those at highest risk.