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New Study Unveils Sex-Based Differences in Pain Receptors

Research reveals distinct nociceptors in males and females, paving the way for sex-specific pain treatments.

  • University of Arizona researchers identified functional differences in nociceptors between sexes.
  • The study found prolactin sensitizes nociceptors in females, while orexin B does so in males.
  • These findings suggest new precision medicine approaches for treating pain in men and women.
  • The research involved tissue samples from mice, nonhuman primates, and humans.
  • The discovery challenges the assumption that pain mechanisms are identical across sexes.
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