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New Study Unveils Brain Signal Disruptions Behind Schizophrenia Voices

Researchers identify faulty brain processes that contribute to auditory hallucinations, offering potential new treatment targets.

Overview

  • Auditory hallucinations in schizophrenia are linked to a failure in suppressing self-generated sounds and an overactive response to internal noises.
  • Key brain processes involved include a 'broken' corollary discharge and a 'noisy' efference copy, leading to confusion between internal and external voices.
  • The study used EEG to compare brain activity in schizophrenia patients with and without auditory hallucinations, revealing distinct neural disruptions.
  • These findings suggest that effective treatments could focus on correcting motor-to-auditory system connections rather than just the auditory system.
  • Researchers propose non-pharmacological interventions, such as transcranial magnetic stimulation, as potential future treatments for resistant cases.