New Study Traces Syphilis Origins to the Americas Before Columbus

Genetic analysis of ancient skeletons supports the theory that syphilis was introduced to Europe from the Americas in the late 15th century.

Researchers analyzed ancient DNA from skeletons in Mexico, Chile, Peru, and Argentina, confirming that syphilis-causing bacteria predated European contact.
The findings bolster the 'Columbian hypothesis,' suggesting syphilis was brought to Europe by Columbus's crew after their expeditions to the Americas.
The study identified genetic relatives of modern syphilis strains circulating in the Americas as far back as 8,000 years ago.
Syphilis, along with related diseases yaws and bejel, likely spread globally through human trafficking and European colonial expansion in the centuries following Columbus's voyages.
While the study provides compelling evidence for an American origin, researchers acknowledge that further investigation is needed to address conflicting evidence of syphilis-like lesions in pre-Columbian European remains.