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New Role of Non-Coding RNA in Accelerating Gene Expression Uncovered

Researchers at the University of Göttingen reveal how antisense RNA boosts protein production by expediting mRNA transport.

  • Antisense RNA (asRNA) pairs with messenger RNA (mRNA) to form double-stranded RNA, enhancing its export from the nucleus to the cytoplasm.
  • This mechanism allows cells to rapidly produce proteins in response to environmental stress or developmental signals.
  • The discovery explains why cells invest significant energy in producing large quantities of asRNA.
  • Understanding asRNA's role opens new avenues for studying disease mechanisms and potential treatments.
  • The findings build on previous research showing mRNA activated under stress bypasses quality control.
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