New Microscopy Technique Enhances Protein Labeling Accuracy
University of Birmingham researchers develop ProDOL to improve protein quantification in living cells, aiding biomedical research.
- ProDOL offers precise determination of labeling efficiencies in microscopy images.
- The technique uses a modular DOL calibration probe for reliable measurements.
- ProDOL's versatility allows application across various cell types and conditions.
- Researchers demonstrated ProDOL's effectiveness in studying HIV-1's impact on immune cells.
- The method could advance understanding of cellular functions in diseases like inflammation and cardiovascular conditions.