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New Microscopy Technique Enhances Protein Labeling Accuracy

University of Birmingham researchers develop ProDOL to improve protein quantification in living cells, aiding biomedical research.

  • ProDOL offers precise determination of labeling efficiencies in microscopy images.
  • The technique uses a modular DOL calibration probe for reliable measurements.
  • ProDOL's versatility allows application across various cell types and conditions.
  • Researchers demonstrated ProDOL's effectiveness in studying HIV-1's impact on immune cells.
  • The method could advance understanding of cellular functions in diseases like inflammation and cardiovascular conditions.
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