Overview

• Researchers at Washington University developed a technique to convert skin cells into brain neurons, mimicking Alzheimer's effects.
• The study identified retrotransposable elements in the genome that change activity with age, contributing to Alzheimer's progression.
• Early intervention with the drug lamivudine showed promise in reducing amyloid beta and tau tangles in lab-grown neurons.
• The research emphasizes the importance of early diagnosis and treatment in managing late-onset Alzheimer's.
• Future studies will explore therapeutic interventions using this new model system.