Particle.news

Download on the App Store

New Method Reveals Aging's Role in Late-Onset Alzheimer's

Scientists transform skin cells into neurons, uncovering key genomic elements and potential early treatments for the disease.

  • Researchers at Washington University developed a technique to convert skin cells into brain neurons, mimicking Alzheimer's effects.
  • The study identified retrotransposable elements in the genome that change activity with age, contributing to Alzheimer's progression.
  • Early intervention with the drug lamivudine showed promise in reducing amyloid beta and tau tangles in lab-grown neurons.
  • The research emphasizes the importance of early diagnosis and treatment in managing late-onset Alzheimer's.
  • Future studies will explore therapeutic interventions using this new model system.
Hero image