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New H3N2 ‘Subclade K’ Drives Early Flu Surges as U.S. Officials Urge Vaccination

Early data show this year’s shot still cuts hospital risk, especially for children.

Overview

  • WHO and national reports say the subclade K offshoot is spreading quickly and now predominates in countries such as the U.K. and Japan.
  • CDC FluView shows most U.S. viruses are influenza A, about 63% are H3N2, and roughly half of analyzed H3N2 samples are subclade K, with pediatric indicators ticking up.
  • An early UK Health Security Agency analysis estimates vaccine effectiveness against hospitalization at about 70–75% for children and 30–40% for adults.
  • U.S. vaccinations are lagging, with about 26.5 million pharmacy doses given Aug–Oct, roughly 2 million fewer than last year, as hospitals and clinicians prepare for a potentially earlier, tougher season.
  • Wastewater and clinical signals point to rising influenza activity, and officials urge vaccination for everyone 6 months and older, prompt antiviral treatment within 48 hours of symptoms, and basic hygiene to reduce spread.